Which factor mainly determines the duration of action of a local anesthetic?
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Correct answer: Protein binding
Drugs with higher protein binding tend to remain attached to sodium channels longer. This prolongs their duration of anesthetic action.
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More Local Anesthetics questions
- Which clinical use is common for local anesthetics?
- Which condition may reduce the effectiveness of local anesthetics?
- Which stage of nerve impulse transmission is blocked by local anesthetics?
- Which local anesthetic is widely used for infiltration anesthesia due to its rapid onset?
- Which outcome best describes the goal of local anesthetic therapy?
- What is the primary mechanism of action of local anesthetics?