Which nerve fibers are most sensitive to local anesthetic blockade?
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Correct answer: Small myelinated fibers
Small myelinated fibers, such as pain fibers (A-delta), are more sensitive to local anesthetics. These fibers are blocked earlier than larger fibers.
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More Local Anesthetics questions
- Which physiological function is lost first when local anesthesia is applied?
- Which factor enhances the effectiveness of local anesthetics?
- Why is epinephrine often added to local anesthetic solutions?
- Which local anesthetic has a long duration of action and is commonly used in epidural anesthesia?
- Which adverse effect may occur with systemic toxicity of local anesthetics?
- Which organ is primarily responsible for the metabolism of amide local anesthetics?