Antiplatelet Drugs · Pharmacology

Which antiplatelet agent acts as a monoclonal antibody against the Glycoprotein IIb/IIIa receptor?

  1. Eptifibatide (Integrilin)
  2. Tirofiban
  3. Abciximab (ReoPro)
  4. Vorapaxar
Show answer and explanation

Correct answer: Abciximab (ReoPro)

Abciximab is the Fab fragment of a chimeric human-murine monoclonal antibody. It binds to the GP IIb/IIIa receptor on the platelet surface, preventing the binding of fibrinogen and von Willebrand factor.

Difficulty: Medium Question 4 of 20

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