Antiplatelet Drugs · Pharmacology

Prasugrel is contraindicated in which of the following patient populations due to an increased risk of intracranial hemorrhage?

  1. Patients diagnosed with Diabetes Mellitus
  2. Patients with prior stroke or TIA history
  3. Patients over the age of 50 years
  4. Patients with documented stable angina pectoris
Show answer and explanation

Correct answer: Patients with prior stroke or TIA history

In clinical trials, Prasugrel was associated with a significant increase in major bleeding, including fatal intracranial hemorrhage, in patients with a prior history of stroke or TIA. Therefore, its use is strictly contraindicated in these individuals.

Difficulty: Medium Question 6 of 20

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