Antiplatelet Drugs · Pharmacology

Unlike Clopidogrel and Prasugrel, Ticagrelor is characterized by which of the following properties?

  1. It binds irreversibly to the P2Y12 receptor
  2. It is a prodrug requiring hepatic activation
  3. It is a reversible P2Y12 receptor antagonist
  4. It primarily inhibits the TXA2 receptor
Show answer and explanation

Correct answer: It is a reversible P2Y12 receptor antagonist

Ticagrelor is a direct-acting, reversible antagonist of the P2Y12 ADP receptor. Because it does not require metabolic activation and binds reversibly, it has a faster onset and offset of action compared to thienopyridines.

Difficulty: Medium Question 3 of 20

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