Ticlopidine is rarely used today primarily due to the risk of which hematologic toxicity?
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Correct answer: Severe Neutropenia and Agranulocytosis
Ticlopidine was the first thienopyridine used clinically, but it caused life-threatening neutropenia in approximately 1% of patients. It has been largely replaced by Clopidogrel, which has a much safer hematologic profile.
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