Which of the following is a Direct Thrombin Inhibitor that is administered parenterally?
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Correct answer: Bivalirudin
Bivalirudin is a synthetic analog of hirudin that binds directly to the active site and exosite of thrombin, and it is given intravenously during percutaneous coronary intervention (PCI) or in patients with a history of HIT. Dabigatran is also a direct thrombin inhibitor, but it is taken orally, while Apixaban and Edoxaban are oral Factor Xa inhibitors.
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