What is the clinical significance of the 'Lupus Anticoagulant' in the context of anticoagulation?
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Correct answer: It is an antibody that prolongs aPTT but increases the risk of thrombosis
Despite its name, the Lupus Anticoagulant is prothrombotic. It interferes with phospholipid-dependent clotting tests in the lab (prolonging aPTT), but in the body, it increases the risk of venous and arterial clots.
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