Anticoagulants · Pharmacology

Andexanet alfa is a decoy molecule designed to reverse the action of which drugs?

  1. Direct Thrombin inhibitors
  2. Vitamin K antagonists
  3. Direct Factor Xa inhibitors
  4. Low Molecular Weight Heparins
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Correct answer: Direct Factor Xa inhibitors

Andexanet alfa is a recombinant modified human Factor Xa protein that acts as a 'decoy' for Factor Xa inhibitors. It binds and sequesters the drug, allowing the patient's endogenous Factor Xa to resume normal coagulation.

Difficulty: Medium Question 11 of 20

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