Which of the following is an indirect-acting sympathomimetic that acts primarily by inhibiting the Reuptake 1 (NET) transporter?
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Correct answer: Cocaine
Cocaine blocks the norepinephrine transporter (NET), preventing the reuptake of norepinephrine into the presynaptic terminal. This results in an accumulation of the neurotransmitter in the synaptic cleft, causing sustained stimulation of adrenergic receptors.
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