Sympathomimetics · Pharmacology

Which of the following sympathomimetics is a non-catecholamine used orally for the treatment of orthostatic hypotension?

  1. Midodrine
  2. Norepinephrine
  3. Dopamine
  4. Epinephrine
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Correct answer: Midodrine

Midodrine is a prodrug converted to the active Alpha-1 agonist desglymidodrine. It increases peripheral vascular resistance and helps maintain blood pressure in patients with autonomic failure, unlike catecholamines which have poor oral bioavailability.

Difficulty: Medium Question 9 of 20

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