Sympathomimetics · Pharmacology

Isoproterenol (Isoprenaline) is unique among catecholamines because it:

  1. Lacks any beta-receptor activity
  2. Is a selective alpha-1 agonist
  3. A potent Beta-1 and Beta-2 agonist with negligible alpha activity
  4. Is used primarily as an oral agent to treat essential hypertension
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Correct answer: A potent Beta-1 and Beta-2 agonist with negligible alpha activity

Isoproterenol is a purely beta-adrenergic agonist. It increases cardiac output (Beta-1) while causing marked peripheral vasodilation (Beta-2), often resulting in a net decrease in mean arterial pressure despite increased heart rate.

Difficulty: Medium Question 10 of 20

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