Cholinergic Agonists · Pharmacology

Which direct-acting agonist is used to stimulate saliva production in patients with Sjögren's syndrome or post-radiation xerostomia?

  1. Cevimeline
  2. Carbachol
  3. Methacholine
  4. Muscarine
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Correct answer: Cevimeline

Cevimeline is a muscarinic agonist with a high affinity for M3 receptors found on salivary and lacrimal glands. It is used to alleviate dry mouth by increasing glandular secretions.

Difficulty: Medium Question 12 of 20

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