Which of the following is true regarding the volume of distribution (Vd) of tetracyclines?
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Correct answer: It is high because they distribute widely into tissues
Tetracyclines are lipophilic and distribute widely into most body fluids and tissues, including the liver, spleen, and bone. They also cross the placental barrier and are excreted in breast milk.
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More Tetracyclines questions
- How should a patient be instructed to take Doxycycline to maximize absorption while minimizing GI upset?
- What is the primary mechanism of action of tetracyclines in inhibiting bacterial growth?
- Which of the following is the most common mechanism of bacterial resistance to tetracyclines?
- Which tetracycline derivative is preferred in patients with renal failure because it is primarily excreted via the bile and feces?
- Why are tetracyclines generally contraindicated in children under the age of 8 and during pregnancy?
- A patient taking Doxycycline for acne develops a severe sunburn-like rash after brief sun exposure. This is an example of which side effect?