Tigecycline has a black box warning regarding which of the following?
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Correct answer: Increased risk of all-cause mortality
Meta-analyses of clinical trials showed an increase in mortality in patients treated with Tigecycline compared to other antibiotics. It is generally reserved for situations where alternative treatments are not suitable.
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More Tetracyclines questions
- In the treatment of periodontitis, sub-antimicrobial doses of Doxycycline are used to inhibit which host enzyme?
- Which of the following is a common supra-infection associated with the use of broad-spectrum tetracyclines?
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- Which of the following is true regarding the volume of distribution (Vd) of tetracyclines?
- How should a patient be instructed to take Doxycycline to maximize absorption while minimizing GI upset?
- What is the primary mechanism of action of tetracyclines in inhibiting bacterial growth?