Why should macrolides be avoided in patients with a history of Myasthenia Gravis?
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Correct answer: They may exacerbate muscle weakness and trigger a myasthenic crisis
Macrolides, especially telithromycin and azithromycin, have been reported to exacerbate symptoms of myasthenia gravis. The mechanism is not fully understood but may involve interference with neuromuscular transmission.
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