Which statement best describes the post-antibiotic effect of macrolides?
Show answer and explanation
Correct answer: They show a marked post-antibiotic effect on Gram-positive cocci
Macrolides exhibit a persistent post-antibiotic effect, where bacterial growth remains suppressed even after the drug concentration falls below the MIC. This supports less frequent dosing intervals for these agents.
Keep practicing
More Macrolides questions
- Erythromycin is frequently used off-label by gastroenterologists to treat which condition?
- Which macrolide has been associated with severe, sometimes fatal, hepatotoxicity and visual disturbances, leading to significant restrictio…
- What is the primary mechanism of action of macrolide antibiotics?
- Which of the following macrolides is known for having a exceptionally long half-life, allowing for a short 3- to 5-day treatment course?
- A patient taking Erythromycin reports significant gastrointestinal cramping and nausea. This is most likely due to the drug's agonism of wh…
- Which of the following is a common cardiovascular side effect associated with macrolide use, especially when combined with other CYP3A4 inh…