Ketolides, such as Telithromycin, were developed specifically to overcome which issue?
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Correct answer: Resistance caused by ribosomal methylation (erm)
Telithromycin is a semi-synthetic derivative of erythromycin that binds to two sites on the bacterial ribosome. This dual binding allows it to remain effective against many strains of S. pneumoniae that are resistant to traditional macrolides.
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