A patient taking Erythromycin reports significant gastrointestinal cramping and nausea. This is most likely due to the drug's agonism of which receptor?
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Correct answer: Motilin receptors
Erythromycin and its metabolites act as agonists at motilin receptors in the gastrointestinal tract. This stimulates migrating motor complexes, leading to increased gastric emptying and intestinal motility, which causes cramping.
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