Fluoroquinolones can cause significant dysglycemia (both hypo- and hyperglycemia), especially in diabetic patients. Which agent was withdrawn from the market largely due to this risk?
Show answer and explanation
Correct answer: Gatifloxacin
Gatifloxacin was associated with severe disturbances in glucose homeostasis. While other fluoroquinolones can cause this, the risk was so pronounced with gatifloxacin that it led to its withdrawal from systemic use.
Keep practicing
More Fluoroquinolones questions
- In the treatment of Anthrax (Bacillus anthracis), which fluoroquinolone is considered a first-line agent for both treatment and post-exposu…
- Which of the following mechanisms contributes to 'plasmid-mediated' quinolone resistance?
- A patient experiences 'brain fog' and peripheral neuropathy after a course of Levofloxacin. These symptoms are part of a syndrome sometimes…
- Which of the following describes the primary mechanism of action of fluoroquinolones in Gram-negative bacteria?
- Which enzyme is the primary target of fluoroquinolones in Gram-positive organisms such as Streptococcus pneumoniae?
- Fluoroquinolones carry a Boxed Warning from the FDA regarding the increased risk of which musculoskeletal complication?