A patient on a fluoroquinolone develops sudden onset of severe abdominal or back pain. The clinician must immediately rule out which rare but catastrophic vascular event?
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Correct answer: Aortic aneurysm rupture or dissection
The FDA has warned that fluoroquinolones can increase the risk of aortic aneurysm or dissection. This is thought to be due to the drug's effect on collagen degradation in the vascular wall.
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