Nafcillin and Oxacillin are primarily used to treat infections caused by:
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Correct answer: Penicillinase-producing Staphylococcus aureus
These are anti-staphylococcal penicillins. Their bulky R-groups prevent binding by staphylococcal beta-lactamases (penicillinases), making them effective against methicillin-susceptible S. aureus (MSSA).
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More Beta-Lactam Antibiotics questions
- A common side effect of oral Amoxicillin/Clavulanate (Augmentin) is diarrhea. This is most often caused by:
- Which of the following is a Fourth-generation cephalosporin that is highly resistant to many beta-lactamases and covers Pseudomonas?
- Which carbapenem is unique because it lacks activity against Pseudomonas aeruginosa and Acinetobacter species?
- The 'Jarisch-Herxheimer reaction' is a systemic inflammatory response sometimes seen after the first dose of penicillin in patients with:
- Which Cephalosporin can cause a disulfiram-like reaction when consumed with alcohol and may lead to vitamin K deficiency?
- Which of the following describes the 'post-antibiotic effect' (PAE) of beta-lactams against Gram-negative bacteria?