Which mechanism explains how echinocandins kill fungal cells?
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Correct answer: Inhibition of fungal cell wall synthesis
Echinocandins inhibit the synthesis of beta-glucan, an essential component of the fungal cell wall. The weakened wall can no longer withstand osmotic pressure, causing cell lysis. Binding to ergosterol in the membrane is the mechanism of amphotericin B, not the echinocandins.
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