Antifungal Drugs · Pharmacology

What is the primary therapeutic goal of antifungal drug therapy?

  1. Suppress the host immune response to fungal antigens
  2. Inhibit or kill fungi while sparing host cells
  3. Eliminate the gut bacteria that compete with fungi
  4. Neutralize circulating fungal toxins
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Correct answer: Inhibit or kill fungi while sparing host cells

Antifungal drugs exploit targets that are unique to fungi, such as ergosterol in the cell membrane or beta-glucan in the cell wall. This selective toxicity lets the drug inhibit or kill the fungus while causing as little damage as possible to human cells.

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