Which antifungal drug binds to ergosterol in fungal cell membranes and forms pores leading to cell death?
Show answer and explanation
Correct answer: Amphotericin B
Amphotericin B binds ergosterol in the fungal cell membrane and forms pores that increase membrane permeability. Leakage of intracellular ions and small molecules follows, killing the fungal cell.
Keep practicing
More Antifungal Drugs questions
- Which antifungal drug class inhibits ergosterol synthesis by blocking the enzyme lanosterol 14-alpha-demethylase?
- Which antifungal drug is commonly used to treat systemic candidiasis?
- Which antifungal drug is mainly used topically for oral candidiasis (thrush)?
- Which antifungal drug interferes with fungal microtubule function and inhibits mitosis?
- Which antifungal drug class inhibits beta-glucan synthesis in the fungal cell wall?
- Which antifungal drug is an echinocandin used for invasive Candida infections?