Antifungal Drugs · Pharmacology

Which antifungal drug class inhibits beta-glucan synthesis in the fungal cell wall?

  1. Azole antifungals
  2. Polyenes
  3. Allylamines
  4. Echinocandins
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Correct answer: Echinocandins

Echinocandins such as caspofungin inhibit the synthesis of beta-1,3-D-glucan, an essential structural polymer of the fungal cell wall. The weakened wall cannot resist osmotic stress and the fungal cell dies.

Difficulty: Medium Question 6 of 20

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