Respiratory Pathology · Pathology

Which paraneoplastic syndrome is most specifically associated with Squamous Cell Carcinoma of the lung?

  1. SIADH (Syndrome of Inappropriate ADH)
  2. Hypercalcemia due to PTHrP production
  3. Cushing syndrome (ACTH production)
  4. Lambert-Eaton myasthenic syndrome
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Correct answer: Hypercalcemia due to PTHrP production

Squamous cell carcinoma frequently produces parathyroid hormone-related protein (PTHrP), which causes hypercalcemia. SIADH and Cushing syndrome are more commonly associated with Small cell carcinoma.

Difficulty: Medium Question 14 of 20

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