A patient with 'Goodpasture Syndrome' will show which pattern on immunofluorescence of the lung biopsy?
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Correct answer: Linear IgG deposits along alveolar basement membranes
Goodpasture syndrome is caused by autoantibodies against the alpha-3 chain of Type IV collagen. Because these antigens are uniformly distributed along the basement membrane, immunofluorescence reveals a smooth, linear pattern.
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