Which microscopic finding is pathognomonic for pseudomembranous colitis caused by Clostridioides difficile?
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Correct answer: Volcano eruption of fibrin, mucin, and neutrophils from crypts
C. difficile toxins cause superficial mucosal necrosis. This results in an inflammatory exudate that erupts from the crypts to form the characteristic yellow-white 'pseudomembranes' on the colonic surface.
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