A biopsy of the small intestine in a patient with Celiac disease would most likely show:
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Correct answer: Villous atrophy with intraepithelial lymphocytosis
Celiac disease is an immune-mediated enteropathy triggered by gluten. Classic histological findings include total or subtotal villous atrophy, crypt hyperplasia, and a marked increase in CD8+ intraepithelial lymphocytes.
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