Gastrointestinal Pathology · Pathology

Which of the following describes the 'Skip Lesions' seen in Crohn disease?

  1. Areas of the bowel that move faster than others during peristalsis
  2. Alternating segments of diseased bowel and normal-appearing bowel
  3. Superficial mucosal ulcers that heal without forming any scar tissue
  4. Hamartomatous polyps that undergo spontaneous regression
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Correct answer: Alternating segments of diseased bowel and normal-appearing bowel

A defining feature of Crohn disease is its segmental distribution. Unlike the continuous involvement of the rectum and colon in Ulcerative Colitis, Crohn's can affect any part of the GI tract with healthy 'skip' areas in between.

Difficulty: Medium Question 13 of 20

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