Which histological finding is considered pathognomonic for Cytomegalovirus (CMV) infection?
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Correct answer: Owl-eye intranuclear inclusion with a perinuclear halo
CMV causes massive cell enlargement (cytomegaly). The characteristic 'owl-eye' appearance is created by a large, purple-to-pink intranuclear inclusion surrounded by a clear halo, often accompanied by smaller cytoplasmic inclusions.
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