Hyperacute transplant rejection occurs within minutes due to pre-existing antibodies. This is fundamentally a form of:
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Correct answer: Type II hypersensitivity
Hyperacute rejection is a Type II reaction where recipient antibodies (e.g., anti-ABO or anti-HLA) immediately bind to the vascular endothelium of the graft, triggering complement activation, thrombosis, and ischemic necrosis.
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