Hypersensitivity Reactions · Pathology

Systemic Anaphylaxis is characterized by which hemodynamic change?

  1. Increased peripheral resistance
  2. Widespread vasodilation and plasma extravasation
  3. Increased cardiac output
  4. Localized hypertension
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Correct answer: Widespread vasodilation and plasma extravasation

Anaphylaxis involves a systemic release of mast cell mediators, leading to massive vasodilation and a sudden drop in blood pressure (shock). Loss of plasma into the interstitial space (edema) further reduces effective circulating volume.

Difficulty: Medium Question 19 of 20

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