Hypersensitivity Reactions Practice Questions
20 free Hypersensitivity Reactions practice questions for the Pathology, each with the correct answer and a detailed explanation. Open any question below, or take the full set as an interactive quiz.
Questions
20 questions
All Hypersensitivity Reactions questions
- Q1. Which of the following mediators, pre-formed in mast cell granules, is primarily responsible for the immediate vasodilation and increased vascular permeability…
- Q2. An Rh-negative mother carries an Rh-positive fetus, leading to hemolytic disease of the newborn. Which hypersensitivity mechanism is responsible for this condi…
- Q3. The 'Arthus reaction' is a localized area of tissue necrosis resulting from acute immune complex vasculitis. This is a classic example of:
- Q4. Which cell type is the primary effector in the 'delayed-type hypersensitivity' (DTH) response, such as the tuberculin skin test?
- Q5. In Graves disease, antibodies bind to the TSH receptor and stimulate thyroid hormone production. This 'stimulatory' variant is classified as which type of hype…
- Q6. Which of the following describes the mechanism of Goodpasture syndrome?
- Q7. Serum sickness is a systemic hypersensitivity reaction that occurs after the administration of foreign proteins. What is the initiating event?
- Q8. Which of the following is a classic example of Type IV hypersensitivity mediated by CD8+ cytotoxic T-lymphocytes (CTLs)?
- Q9. What is the role of the 'early phase' in Type I hypersensitivity?
- Q10. Fibrinoid necrosis in small blood vessels is a histological hallmark of which hypersensitivity reaction?
- Q11. Which cytokine is essential for the 'isotype switching' of B-cells to IgE in Type I hypersensitivity?
- Q12. The 'lumpy-bumpy' or granular pattern of immunofluorescence in Post-Streptococcal Glomerulonephritis indicates:
- Q13. Which of the following clinical scenarios involves a 'hapten' mechanism causing Type IV hypersensitivity?
- Q14. Myasthenia gravis involves antibodies that inhibit a receptor without causing cell lysis. Which receptor is targeted?
- Q15. Which of the following is the 'late-phase' effector cell most associated with chronic allergic inflammation?
- Q16. In Type III hypersensitivity, what is the primary cause of neutrophilic recruitment to the site of immune complex deposition?
- Q17. Farmers' lung (Hypersensitivity Pneumonitis) is a complex reaction often involving both:
- Q18. Which molecule on the surface of sensitized T-cells binds to the 'Fas' receptor on target cells to induce apoptosis in Type IV hypersensitivity?
- Q19. Systemic Anaphylaxis is characterized by which hemodynamic change?
- Q20. Hyperacute transplant rejection occurs within minutes due to pre-existing antibodies. This is fundamentally a form of: