Tissue shrinkage during processing is most often due to:
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Correct answer: Excessive dehydration with alcohol
Excessive dehydration during processing causes tissue shrinkage and separation artifacts. Alcohol removes water aggressively, leading to distortion of tissue architecture.
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More Artifacts in Histology questions
- Knife lines seen across a histologic section are typically caused by:
- Formalin pigment (acid hematin) is most likely to appear in tissues fixed with:
- Tissue folds observed in a section are most commonly due to:
- Air bubbles trapped under the coverslip are classified as:
- Chatter or "venetian blind" artifact is typically caused by:
- Overfixation of tissue in formalin may lead to: