Which precursor protein is responsible for AA amyloid formation?
Show answer and explanation
Correct answer: Serum amyloid A protein
AA amyloid is derived from serum amyloid A protein, an acute-phase reactant produced by the liver during chronic inflammation. Persistent elevation leads to misfolding and deposition.
Keep practicing
More Amyloidosis questions
- Dialysis-associated amyloidosis is primarily due to accumulation of which protein?
- Which cardiac manifestation is commonly seen in patients with systemic amyloidosis?
- Hereditary amyloidosis due to mutant transthyretin most often affects which system?
- Which histologic pattern is typical of amyloid deposition in the spleen?
- The pathogenesis of amyloidosis primarily involves which mechanism?
- Which staining technique besides Congo red can demonstrate amyloid deposits?