Peptic Ulcer Disease · Pathology

Which histological layer of a classic peptic ulcer is characterized by the presence of neutrophils and fibrinopurulent exudate?

  1. Superficial zone of necrosis
  2. Zone of active inflammation
  3. Zone of granulation tissue
  4. Zone of fibrous scarring
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Correct answer: Zone of active inflammation

A peptic ulcer has four distinct layers. Beneath the superficial necrotic debris lies a zone of active inflammation dominated by neutrophils, followed by granulation tissue and a deeper layer of collagenous scar.

Difficulty: Medium Question 4 of 20

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