Peptic Ulcer Disease · Pathology

The presence of 'coffee-ground' emesis in a patient with a known peptic ulcer indicates which complication?

  1. Perforation
  2. Hemorrhage
  3. Pyloric stenosis
  4. Malignant transformation
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Correct answer: Hemorrhage

Coffee-ground emesis is caused by the reaction of blood with gastric acid, which oxidizes the iron in hemoglobin to hematin. This is a classic sign of upper gastrointestinal bleeding from an ulcer.

Difficulty: Medium Question 8 of 20

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