Zollinger-Ellison syndrome causes multiple peptic ulcers due to a tumor secreting which hormone?
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Correct answer: Gastrin
Zollinger-Ellison syndrome is caused by a gastrin-secreting tumor (gastrinoma), usually in the pancreas or duodenum. The resulting massive hypersecretion of gastric acid leads to severe, often multiple, recalcitrant peptic ulcers.
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