Which antibody is most frequently associated with Ulcerative Colitis?
Show answer and explanation
Correct answer: Perinuclear anti-neutrophil cytoplasmic antibodies (pANCA)
pANCA is positive in approximately 60-75% of patients with Ulcerative Colitis. Conversely, ASCA is more commonly found in patients with Crohn disease.
Keep practicing
More Inflammatory Bowel Disease questions
- Why is the risk of adenocarcinoma higher in Ulcerative Colitis compared to the general population?
- Which region of the gastrointestinal tract is most commonly involved in Crohn disease?
- What is the primary genetic association found in many patients with Crohn disease, involving intracellular bacteria sensing?
- Which of the following is true regarding smoking and IBD?
- Which of the following is a classic microscopic feature of 'chronic' IBD that indicates long-standing injury?
- Fissures in the bowel wall are most likely to lead to which clinical finding in Crohn disease?