Inflammatory Bowel Disease · Pathology

Which of the following describes the distribution of inflammation in Crohn disease?

  1. Superficial and limited to the mucosa
  2. Transmural, involving all layers of the bowel wall
  3. Limited only to the sigmoid colon and rectum
  4. Exclusively involves the serosa and muscularis propria
Show answer and explanation

Correct answer: Transmural, involving all layers of the bowel wall

Crohn disease features transmural inflammation, which contributes to the development of complications like fistulas, sinus tracts, and strictures. Ulcerative Colitis is typically limited to the mucosa and submucosa.

Difficulty: Medium Question 3 of 20

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