A 45-year-old obese male is diagnosed with Type 2 Diabetes Mellitus. Which of the following is the hallmark of the early stage of this disease?
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Correct answer: Insulin resistance with hyperinsulinemia
Type 2 Diabetes begins with insulin resistance in peripheral tissues like muscle and fat. Initially, the pancreas compensates by secreting more insulin (hyperinsulinemia) to maintain normal glucose levels before eventually failing.
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