Nerve Regeneration · Histology

Which neurotrophic factor is highly expressed by Schwann cells following a nerve injury to support axonal survival?

  1. Insulin
  2. Glial Fibrillary Acidic Protein
  3. Nerve Growth Factor (NGF)
  4. Acetylcholinesterase
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Correct answer: Nerve Growth Factor (NGF)

Following injury, Schwann cells increase the production of neurotrophins like Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF). These factors bind to receptors on the axonal growth cone to promote survival and guidance.

Difficulty: Medium Question 9 of 20

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