What is the role of the 'basal lamina' of the Schwann cell during regeneration?
Show answer and explanation
Correct answer: It serves as a scaffold for the regenerating axon
The Schwann cell basal lamina persists after the axon and myelin have degenerated. It contains laminin and fibronectin, providing a supportive substrate that guides the regenerating axon back to its target.
Keep practicing
More Nerve Regeneration questions
- Which type of axonal transport is responsible for moving the materials required for building the new axonal cytoskeleton during repair?
- If an axon was previously myelinated, what happens after it successfully regenerates?
- Following denervation, what characteristic change occurs in the target skeletal muscle?
- Which molecule found in CNS myelin is a major inhibitor of axonal outgrowth?
- Transneuronal (transsynaptic) degeneration refers to:
- The success of peripheral nerve regeneration is most dependent on which factor?