Nerve Regeneration · Histology

In the CNS, the formation of a 'glial scar' is primarily attributed to which cell type?

  1. Ependymal cells
  2. Perivascular macrophages
  3. Reactive astrocytes
  4. Satellite cells
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Correct answer: Reactive astrocytes

Reactive astrogliosis occurs after CNS injury, where astrocytes proliferate and extend processes to wall off the injury site. This physical and chemical barrier (the glial scar) prevents axonal regeneration.

Difficulty: Medium Question 10 of 20

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