Nerve Regeneration · Histology

Which of the following describes 'Retrograde Degeneration' in a damaged neuron?

  1. Degeneration of the distal axon segment
  2. Death of the neighboring healthy neurons
  3. Degeneration of the proximal axon segment
  4. Breakdown of the myelin sheath at the injury site
Show answer and explanation

Correct answer: Degeneration of the proximal axon segment

Retrograde degeneration is the breakdown of the proximal portion of the axon, extending from the site of injury back toward the first node of Ranvier. It usually involves only a few internodes.

Difficulty: Medium Question 12 of 20

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