A desmosome (macula adherens) is histologically characterized by its attachment to which cytoskeletal element?
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Correct answer: Intermediate filaments (keratin)
Desmosomes are 'spot' adhesions that provide intense mechanical strength. They are anchored to intermediate filaments (cytokeratins in epithelial cells) via an intracellular plaque of proteins like desmoplakin and plakoglobin.
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