Cell Junctions · Histology

Which junctional complex component is responsible for maintaining the 'apical-basolateral polarity' of epithelial cells?

  1. Zonula adherens
  2. Zonula occludens
  3. Macula occludens
  4. Fascia adherens
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Correct answer: Zonula occludens

By forming a physical barrier within the lipid bilayer, zonula occludens (tight junctions) prevent the lateral diffusion of integral membrane proteins. This ensures that apical proteins remain on the apical surface and basolateral proteins remain on the sides and bottom.

Difficulty: Medium Question 11 of 20

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