Digestive Mucosa · Histology

Chief cells (zymogenic cells) of the stomach are primarily located in which part of the gastric gland?

  1. Isthmus
  2. Neck
  3. Base
  4. Surface
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Correct answer: Base

Chief cells occupy the lower part of the gastric glands in the fundus and body. They contain granules of pepsinogen, which is released and then converted to active pepsin by the acidic environment of the stomach.

Difficulty: Medium Question 15 of 20

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